Elevated urinary levels of kidney injury molecule-1 among Chinese factory workers exposed to trichloroethylene
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چکیده
منابع مشابه
Elevated urinary levels of kidney injury molecule-1 among Chinese factory workers exposed to trichloroethylene.
Epidemiological studies suggest that trichloroethylene (TCE) exposure may be associated with renal cancer. The biological mechanisms involved are not exactly known although nephrotoxicity is believed to play a role. Studies on TCE nephrotoxicity among humans, however, have been largely inconsistent. We studied kidney toxicity in Chinese factory workers exposed to TCE using novel sensitive nephr...
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Trichloroethylene (TCE) is an important volatile organic compound once widely used in industry throughout the world. Occupational exposure to TCE can cause a number of health hazards such as allergic reactions and genetic damage. The purpose of this study was to evaluate occupational exposure to TCE, by analysis of the air in the breathing zone and of urine from workers employed in a clock manu...
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PURPOSE Kidney Injury Molecule-1 is a protein that increases in urine following tubular damage. Kidney Injury Molecule-1 levels were correlated with the level of chronic kidney disease secondary to diabetic nephropathy in patients with type 2 Diabetes Mellitus. METHODS Clinical and laboratory findings of 142 patients with diabetic nephropathy and 34 control subjects were analysed. Creatinine ...
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Chlorobenzene is a colorless volatile compound widely used as an organic solvent or a chemical intermediate. There is, however, a potential risk for people engaged in the manufacture and the handling of this compound. The threshold limit value of the time-weighted average (TLV-TWA) for chlorobenzene in air has been set at 75 ppm (350 mg/m3).1) Animals exposed to chlorobenzene excrete this compo...
متن کاملDiagnostic Value of Urinary Kidney Injury Molecule 1 for Acute Kidney Injury: A Meta-Analysis
BACKGROUND Urinary Kidney Injury Molecule 1 (KIM-1) is a proximal tubular injury biomarker for early detection of acute kidney injury (AKI), with variable performance characteristics depending on clinical and population settings. METHODS Meta-analysis was performed to assess the diagnostic value of urinary KIM-1 in AKI. Relevant studies were searched from MEDLINE, EMBASE, Pubmed, Elsevier Sci...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2012
ISSN: 0143-3334,1460-2180
DOI: 10.1093/carcin/bgs191